Ligand Data Base
Here you will find information from the ChEMBL database on known ligands interacting with the proteins in the
Swiss-PO database. A search by gene name or ChEMBL identifier is available.
For each molecule, links are provided to bioinformatics tools enabling the user to carry out further analyses:
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ABCB1 ABL1 ABL2 ACVR1 ACVR1B ACVR2A AKT1 AKT2 AKT3 ALB ALDH2 ALK APLNR AR ARAF ATM ATXN2 AURKA AURKB AURKC AXL BCL2 BCL2L2 BCR BLM BRAF BRD4 BRD7 BRSK1 BTK CARS1 CBFB CCND1 CCNE1 CDK12 CDK4 CDK6 CDK8 CHD4 CHEK1 CHEK2 CHUK CRBN CSF1R CSNK1A1 CYP19A1 CYP2C19 CYP2D6 DDR1 DDR2 DDX3X DYRK1A EGFR EPHA2 EPHA3 EPHA5 EPHA6 EPHA7 EPHB4 ERBB2 ERBB4 ERCC2 ESR1 EZH2 FES FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT3 FRK FYN G6PD GNB1 GRIN2A GRM3 GSK3B HDAC1 HDAC2 HDAC4 HDAC7 HDAC9 HIF1A HMGCR HSP90AA1 HSP90AB1 ICK IDH1 IGF1R IKBKB IKBKE INSR ITGB3 ITK JAK1 JAK2 JAK3 KCNJ5 KDR KIT KMT2A LATS2 LCK LMNA LRRK2 LTK LYN MAP2K1 MAP2K2 MAP2K7 MAP3K1 MAP3K11 MAP3K13 MAP3K14 MAP3K4 MAP3K6 MAP3K7 MAP4K4 MAPK1 MAPK3 MAPK8 MARK1 MARK2 MARK4 MDN1 MEN1 MERTK MET MGAM MKNK1 MMP2 MST1R MTOR NCSTN NFE2L2 NFKB1 NFKB2 NQO1 NTRK2 NTRK3 PAK1 PAK3 PAK7 PARP2 PASK PAX8 PDE3A PDGFRA PDGFRB PDPK1 PGR PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIM1 PLK2 POU2F2 PPARG PRKACA PRKCI PRKD1 PRKD2 PSMB2 PTGS2 PTK6 PTPN1 PTPN11 PTPRC RAC1 RAF1 RECQL RET RIOK2 ROCK2 ROS1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KB1 RUNX1 RXRA SEPTIN9 SGK1 SMAD3 SMC1A SRC STAT1 STAT3 STK11 SYK TAOK1 TAOK2 TEC TEK TERT TGFBR1 TNK2 TOP1 TOP2A TP53 TRIM24 TRIM33 TRKA TSHR TTK TYK2 TYRO3 UGT1A1 VHL WEE1 WNK1 YES1
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CHEMBL10 CHEMBL101253 CHEMBL103 CHEMBL103104 CHEMBL103667 CHEMBL105350 CHEMBL106124 CHEMBL1065 CHEMBL1069 CHEMBL1071 CHEMBL107251 CHEMBL1073 CHEMBL1077604 CHEMBL1079175 CHEMBL1080441 CHEMBL1082 CHEMBL1082407 CHEMBL1084546 CHEMBL1086747 CHEMBL1089641 CHEMBL1091 CHEMBL1093264 CHEMBL1094 CHEMBL1096290 CHEMBL1096626 CHEMBL1096634 CHEMBL1116 CHEMBL1144 CHEMBL116438 CHEMBL1172317 CHEMBL1177 CHEMBL118 CHEMBL1182210 CHEMBL119385 CHEMBL1197051 CHEMBL1200374 CHEMBL1200391 CHEMBL1200485 CHEMBL1200492 CHEMBL1200656 CHEMBL1200865 CHEMBL1201010 CHEMBL1201022 CHEMBL1201049 CHEMBL1201087 CHEMBL1201139 CHEMBL1201147 CHEMBL1201199 CHEMBL1201235 CHEMBL121 CHEMBL1214598 CHEMBL1215 CHEMBL1230609 CHEMBL1231530 CHEMBL1232132 CHEMBL1232461 CHEMBL123292 CHEMBL1233528 CHEMBL1235969 CHEMBL1236107 CHEMBL1236682 CHEMBL1236962 CHEMBL1243 CHEMBL1255901 CHEMBL1256017 CHEMBL1256910 CHEMBL1263 CHEMBL1272 CHEMBL1277662 CHEMBL128000 CHEMBL1289494 CHEMBL1289601 CHEMBL1289926 CHEMBL129795 CHEMBL13045 CHEMBL1308 CHEMBL1314376 CHEMBL13209 CHEMBL1329455 CHEMBL1358 CHEMBL1371937 CHEMBL1374360 CHEMBL14090 CHEMBL1409791 CHEMBL1410943 CHEMBL14112 CHEMBL1421 CHEMBL14249 CHEMBL1430 CHEMBL1448 CHEMBL1451 CHEMBL14762 CHEMBL1479 CHEMBL1484 CHEMBL1501 CHEMBL1503 CHEMBL15137 CHEMBL1516890 CHEMBL1517 CHEMBL1526572 CHEMBL153062 CHEMBL154111 CHEMBL1554 CHEMBL1557 CHEMBL1560 CHEMBL1566956 CHEMBL1567463 CHEMBL157101 CHEMBL16 CHEMBL16068 CHEMBL1614641 CHEMBL1614701 CHEMBL1614713 CHEMBL1641668 CHEMBL1642 CHEMBL1643772 CHEMBL1645462 CHEMBL1651534 CHEMBL1661 CHEMBL1667969 CHEMBL1670 CHEMBL168 CHEMBL1684 CHEMBL169 CHEMBL170988 CHEMBL1710 CHEMBL1721885 CHEMBL1725279 CHEMBL17331 CHEMBL1750 CHEMBL1751 CHEMBL1752 CHEMBL1756 CHEMBL177756 CHEMBL178 CHEMBL1789941 CHEMBL1789961 CHEMBL1789962 CHEMBL179166 CHEMBL179311 CHEMBL1794050 CHEMBL1794052 CHEMBL1794057 CHEMBL1794060 CHEMBL1794061 CHEMBL1794064 CHEMBL1794065 CHEMBL1794066 CHEMBL1794068 CHEMBL1794069 CHEMBL1794070 CHEMBL1794073 CHEMBL179453 CHEMBL179465 CHEMBL180022 CHEMBL180101 CHEMBL1823872 CHEMBL1834184 CHEMBL1834657 CHEMBL184 CHEMBL185 CHEMBL185939 CHEMBL186054 CHEMBL186213 CHEMBL187081 CHEMBL1873475 CHEMBL1879463 CHEMBL1880739 CHEMBL188426 CHEMBL1885746 CHEMBL188784 CHEMBL188794 CHEMBL189 CHEMBL189148 CHEMBL189353 CHEMBL189415 CHEMBL189459 CHEMBL1908355 CHEMBL1908391 CHEMBL1908394 CHEMBL1908397 CHEMBL1909056 CHEMBL1909072 CHEMBL1909073 CHEMBL1909350 CHEMBL1909351 CHEMBL1909352 CHEMBL1909355 CHEMBL1909356 CHEMBL1909358 CHEMBL1909359 CHEMBL1909360 CHEMBL1909361 CHEMBL1909362 CHEMBL1909363 CHEMBL1909364 CHEMBL1909368 CHEMBL1909369 CHEMBL1909370 CHEMBL1909373 CHEMBL1909374 CHEMBL1909380 CHEMBL1909381 CHEMBL1909382 CHEMBL1909383 CHEMBL1909385 CHEMBL1909391 CHEMBL1909392 CHEMBL1909395 CHEMBL1909396 CHEMBL1909398 CHEMBL1909399 CHEMBL1909402 CHEMBL1909403 CHEMBL1909405 CHEMBL1909408 CHEMBL1909409 CHEMBL1909415 CHEMBL191003 CHEMBL19163 CHEMBL191705 CHEMBL19224 CHEMBL192417 CHEMBL1939876 CHEMBL194062 CHEMBL1944698 CHEMBL1946170 CHEMBL195185 CHEMBL1952329 CHEMBL196022 CHEMBL1971943 CHEMBL2 CHEMBL201511 CHEMBL2018302 CHEMBL202891 CHEMBL2029988 CHEMBL2035185 CHEMBL2035187 CHEMBL2041933 CHEMBL204232 CHEMBL2048484 CHEMBL204934 CHEMBL205158 CHEMBL205596 CHEMBL205765 CHEMBL205798 CHEMBL206010 CHEMBL206834 CHEMBL207247 CHEMBL2074769 CHEMBL2103774 CHEMBL2103842 CHEMBL2103882 CHEMBL2105717 CHEMBL2107456 CHEMBL212250 CHEMBL2133806 CHEMBL2137046 CHEMBL2146883 CHEMBL215152 CHEMBL2152944 CHEMBL215814 CHEMBL215993 CHEMBL2170610 CHEMBL217092 CHEMBL2180604 CHEMBL218720 CHEMBL218859 CHEMBL218932 CHEMBL218969 CHEMBL220244 CHEMBL221137 CHEMBL2219422 CHEMBL221959 CHEMBL222102 CHEMBL222419 CHEMBL223360 CHEMBL230001 CHEMBL230011 CHEMBL230911 CHEMBL231013 CHEMBL231623 CHEMBL23194 CHEMBL2323775 CHEMBL2333546 CHEMBL235191 CHEMBL23588 CHEMBL2364611 CHEMBL238071 CHEMBL238188 CHEMBL2393130 CHEMBL243907 CHEMBL247228 CHEMBL24828 CHEMBL249697 CHEMBL251549 CHEMBL253969 CHEMBL257113 CHEMBL258805 CHEMBL259112 CHEMBL259389 CHEMBL26 CHEMBL260138 CHEMBL261131 CHEMBL261849 CHEMBL265502 CHEMBL266487 CHEMBL267345 CHEMBL267744 CHEMBL268291 CHEMBL268368 CHEMBL268885 CHEMBL269538 CHEMBL269827 CHEMBL269883 CHEMBL270054 CHEMBL270544 CHEMBL270687 CHEMBL271594 CHEMBL272026 CHEMBL272414 CHEMBL273564 CHEMBL274064 CHEMBL274654 CHEMBL274893 CHEMBL274990 CHEMBL275079 CHEMBL275473 CHEMBL275707 CHEMBL275742 CHEMBL276711 CHEMBL276915 CHEMBL27759 CHEMBL278041 CHEMBL278315 CHEMBL278590 CHEMBL278724 CHEMBL279229 CHEMBL281872 CHEMBL282042 CHEMBL282433 CHEMBL284116 CHEMBL28509 CHEMBL286398 CHEMBL286721 CHEMBL288441 CHEMBL294199 CHEMBL295316 CHEMBL296468 CHEMBL296586 CHEMBL297792 CHEMBL300982 CHEMBL302449 CHEMBL303846 CHEMBL3039525 CHEMBL30432 CHEMBL305477 CHEMBL306498 CHEMBL306865 CHEMBL30707 CHEMBL307429 CHEMBL310798 CHEMBL3115681 CHEMBL3120215 CHEMBL3137331 CHEMBL3137336 CHEMBL314854 CHEMBL3182621 CHEMBL3183075 CHEMBL3184679 CHEMBL3186534 CHEMBL3186993 CHEMBL318728 CHEMBL319244 CHEMBL3218576 CHEMBL325041 CHEMBL327919 CHEMBL328250 CHEMBL3286797 CHEMBL3287255 CHEMBL3287735 CHEMBL3301610 CHEMBL3301612 CHEMBL331237 CHEMBL332794 CHEMBL3337894 CHEMBL3342332 CHEMBL3360203 CHEMBL33845 CHEMBL3417525 CHEMBL34241 CHEMBL34259 CHEMBL350221 CHEMBL3544964 CHEMBL3545083 CHEMBL3545137 CHEMBL3545154 CHEMBL3545307 CHEMBL3545308 CHEMBL3545311 CHEMBL3545360 CHEMBL3577885 CHEMBL3582461 CHEMBL3582478 CHEMBL3589752 CHEMBL359744 CHEMBL359999 CHEMBL36 CHEMBL361237 CHEMBL3617968 CHEMBL3621988 CHEMBL3623290 CHEMBL363648 CHEMBL364804 CHEMBL36506 CHEMBL365248 CHEMBL365297 CHEMBL365663 CHEMBL3670685 CHEMBL3685796 CHEMBL3701197 CHEMBL3707348 CHEMBL37161 CHEMBL372474 CHEMBL372764 CHEMBL373751 CHEMBL374060 CHEMBL374478 CHEMBL374975 CHEMBL377300 CHEMBL379300 CHEMBL3797887 CHEMBL3799292 CHEMBL3799512 CHEMBL3813842 CHEMBL3818247 CHEMBL381948 CHEMBL382590 CHEMBL3833319 CHEMBL38380 CHEMBL383899 CHEMBL384407 CHEMBL384467 CHEMBL386630 CHEMBL388978 CHEMBL3907479 CHEMBL3916717 CHEMBL391997 CHEMBL396107 CHEMBL3963485 CHEMBL397591 CHEMBL3987016 CHEMBL3989868 CHEMBL3989927 CHEMBL40 CHEMBL402108 CHEMBL404849 CHEMBL405042 CHEMBL405130 CHEMBL4059888 CHEMBL406117 CHEMBL4071161 CHEMBL4081711 CHEMBL4084907 CHEMBL4085457 CHEMBL409 CHEMBL4093612 CHEMBL4098877 CHEMBL409892 CHEMBL4100408 CHEMBL413 CHEMBL413188 CHEMBL413965 CHEMBL4165749 CHEMBL417799 CHEMBL418971 CHEMBL419564 CHEMBL4228713 CHEMBL423192 CHEMBL42485 CHEMBL426800 CHEMBL427159 CHEMBL428 CHEMBL4282264 CHEMBL428690 CHEMBL4298169 CHEMBL434729 CHEMBL435 CHEMBL435176 CHEMBL440687 CHEMBL441702 CHEMBL442363 CHEMBL443563 CHEMBL443684 CHEMBL4445670 CHEMBL444633 CHEMBL445 CHEMBL4455582 CHEMBL445813 CHEMBL4458424 CHEMBL446 CHEMBL44657 CHEMBL4483575 CHEMBL45 CHEMBL450071 CHEMBL450786 CHEMBL4513786 CHEMBL451532 CHEMBL4516471 CHEMBL4518706 CHEMBL4521594 CHEMBL4522773 CHEMBL4522930 CHEMBL4526351 CHEMBL4526356 CHEMBL452861 CHEMBL4530401 CHEMBL4530740 CHEMBL4531220 CHEMBL4531334 CHEMBL4531775 CHEMBL4533479 CHEMBL4534005 CHEMBL4535474 CHEMBL4536197 CHEMBL4537673 CHEMBL4537788 CHEMBL4538591 CHEMBL4540759 CHEMBL4546802 CHEMBL4551344 CHEMBL455518 CHEMBL456 CHEMBL4560241 CHEMBL4560589 CHEMBL456252 CHEMBL4564312 CHEMBL4566600 CHEMBL4568183 CHEMBL456881 CHEMBL4578164 CHEMBL4580220 CHEMBL458415 CHEMBL458438 CHEMBL4584981 CHEMBL4585243 CHEMBL4585920 CHEMBL4586794 CHEMBL4587626 CHEMBL458865 CHEMBL4588900 CHEMBL461522 CHEMBL4630641 CHEMBL463981 CHEMBL46469 CHEMBL4648362 CHEMBL465843 CHEMBL466412 CHEMBL46740 CHEMBL467581 CHEMBL467888 CHEMBL46874 CHEMBL468870 CHEMBL468963 CHEMBL469 CHEMBL471789 CHEMBL473629 CHEMBL475251 CHEMBL475761 CHEMBL476259 CHEMBL476351 CHEMBL477069 CHEMBL477182 CHEMBL477583 CHEMBL477772 CHEMBL477978 CHEMBL477979 CHEMBL478629 CHEMBL479038 CHEMBL479079 CHEMBL4802046 CHEMBL480371 CHEMBL480382 CHEMBL481310 CHEMBL481510 CHEMBL482326 CHEMBL482967 CHEMBL48310 CHEMBL483158 CHEMBL483254 CHEMBL483321 CHEMBL483747 CHEMBL485745 CHEMBL485980 CHEMBL486124 CHEMBL491 CHEMBL491473 CHEMBL494089 CHEMBL495696 CHEMBL495727 CHEMBL495771 CHEMBL495902 CHEMBL496102 CHEMBL50 CHEMBL500 CHEMBL502835 CHEMBL503 CHEMBL504936 CHEMBL505187 CHEMBL50588 CHEMBL505915 CHEMBL505927 CHEMBL506414 CHEMBL506929 CHEMBL507329 CHEMBL508338 CHEMBL509032 CHEMBL5095220 CHEMBL513330 CHEMBL513909 CHEMBL514162 CHEMBL514201 CHEMBL514499 CHEMBL514938 CHEMBL515914 CHEMBL516 CHEMBL517123 CHEMBL517171 CHEMBL517907 CHEMBL517986 CHEMBL518953 CHEMBL518968 CHEMBL519881 CHEMBL521 CHEMBL521179 CHEMBL521806 CHEMBL521851 CHEMBL522892 CHEMBL524057 CHEMBL524901 CHEMBL531804 CHEMBL532 CHEMBL535 CHEMBL536151 CHEMBL54440 CHEMBL547 CHEMBL54909 CHEMBL553 CHEMBL555017 CHEMBL558 CHEMBL561132 CHEMBL56337 CHEMBL564 CHEMBL564829 CHEMBL57 CHEMBL572878 CHEMBL572881 CHEMBL574737 CHEMBL574738 CHEMBL575060 CHEMBL575448 CHEMBL576982 CHEMBL577784 CHEMBL580 CHEMBL588025 CHEMBL593229 CHEMBL595 CHEMBL6 CHEMBL601719 CHEMBL603469 CHEMBL607707 CHEMBL60889 CHEMBL620 CHEMBL6246 CHEMBL6273 CHEMBL628 CHEMBL633 CHEMBL63728 CHEMBL640 CHEMBL64391 CHEMBL64925 CHEMBL65 CHEMBL654 CHEMBL66004 CHEMBL666 CHEMBL67241 CHEMBL679 CHEMBL682 CHEMBL691 CHEMBL6966 CHEMBL713 CHEMBL71685 CHEMBL717 CHEMBL723 CHEMBL729 CHEMBL73234 CHEMBL7463 CHEMBL75094 CHEMBL762 CHEMBL7724 CHEMBL77456 CHEMBL786 CHEMBL79 CHEMBL807 CHEMBL81 CHEMBL8145 CHEMBL84 CHEMBL84158 CHEMBL848 CHEMBL87223 CHEMBL878 CHEMBL8809 CHEMBL894 CHEMBL89598 CHEMBL897 CHEMBL898 CHEMBL9 CHEMBL90555 CHEMBL90593 CHEMBL91 CHEMBL91153 CHEMBL91829 CHEMBL923 CHEMBL932 CHEMBL939 CHEMBL941 CHEMBL960 CHEMBL98 CHEMBL98350 CHEMBL986
This table presents relevant information on molecules that can bind to proteins, such as their binding affinity.
The ChEMBL and UniPROT identifiers are provided, and clicking on it will open the corresponding web page.
Clicking on one of the icons in the cell corresponding to the ligand takes you to the web page pre-filled with
the SMILES of the ligand in the corresponding tool. Rows can be filtered up or down by clicking on the column headers